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From the diagnostic investigations of goiter to the diagnosis of lung cancer – case study

Monika Koziołek1, Anna Sieradzka1*, Lilianna Osowicz-Korolonek1, Ewa Wentland-Kotwicka2, Katarzyna Karpińska-Kaczmarczyk3 and Anhelli Syrenicz1

Author Affiliations

1 Department of Endocrinology, Metabolic Diseases and Internal Diseases, Pomeranian Medical University in Szczecin, Szczecin, Poland

2 Clinical Specialized Ambulatory of Endocrinology, Autonomous Public Clinical Hospital No. 1 of Pomeranian Medical University in Szczecin, Szczecin, Poland

3 Department of Patomorphology, Pomeranian Medical University in Szczecin, Szczecin, Poland

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Thyroid Research 2014, 7:1  doi:10.1186/1756-6614-7-1

Published: 1 February 2014


Thyroid metastases account for approximately 1.4-3% of all malignancies of the thyroid gland. Thyroid metastases are most common in: clarocellular carcinoma of the kidney, lung cancer, breast cancer, malignant melanoma and cancers of gastrointestinal tract. A rare situation is when thyroid metastasis is diagnosed before detecting primary malignant focus and when it is the first manifestation of underlying disease. We present a case of 64-year-old male with thyroid metastasis being the first manifestation of lung adenocarcinoma.

The authors emphasize that patients with the history of malignancy should undergo an ultrasound examination of the thyroid gland in order to exclude a focal lesion, and if such lesion is detected, fine-needle aspiration biopsy is recommended. The authors also point out that establishing final diagnosis of thyroid metastasis of cancer in other organs is only possible on the basis of postoperative histopathology and immunohistochemistry.

Thyroid metastases; Lung cancer; Histopathology; Immunohistochemistry